(Correction: We previously reported the closure was 22 hours when it was actually 10 hours.)

(KLAS) – After a 10-hour closure, the I-15 lanes south of Sloan reopened to traffic Tuesday morning around 4 a.m. The southbound lanes were closed due to a fiery crash involving six vehicles that left four people dead and two others injured.

According to Nevada State Police, a woman driving alone in a red Cadillac was driving north in the southbound lanes of I-15 between Sloan and Jean when she collided head-on with a Toyota pickup truck in a southbound lane with three people inside. The Toyota burst into flames killing all three occupants. The woman in the Cadillac was also killed.

Police say a Toyota pickup (left) was hit head-on by the red Cadillac (right) which was driving the wrong direction on I-15 in-between Sloan and Jean. The female driver of the Cadillac and the three people in the Toyota were killed in this crash. (Photographs: Samuel Gilbert)

The crash was reported around 6 p.m. Monday night.

“There is evidence on scene to believe that alcohol may have played a factor in this crash,” said Trooper Ashlee Wellman.

(Image: KLAS)

Nevada State Police say four other vehicles were involved in the crash including a semi-truck that swerved to avoid the crash scene, a pickup truck, a Volvo, and a Kia. The drivers of the Volvo and Kia were injured and transported to the hospital. They are expected to recover. The two other drivers were not injured.

Throughout the night, drivers on I-15 southbound were diverted off the freeway while the crash scene was under investigation.

These are the first fatalities of 2022 to be investigated by Nevada State Police in Southern Nevada.