William Carrier put Vegas ahead for good after Ottawa rallied from a three-goal deficit, and the Golden Knights beat the Senators 5-3 on Thursday night.
Jonathan Marchessault, Shea Theodore, Nick Holden and Pierre-Edouard Bellemare also scored for the Golden Knights. Marc-Andre Fleury made 27 saves.
Matt Duchene, Ryan Dzingel and Thomas Chabot scored for the Senators, who fell behind 3-0 late in the second period before coming back to tie it in the third. Craig Anderson stopped 37 shots.
Trailing 3-1 to start the third, Ottawa scored twice in just over a minute to make it 3-3. Dzingel scored at 6:57, and Chabot converted into a wide-open net as Fleury was caught sprawling.
Vegas regained the lead about a minute later as Carrier won a battle along the boards, stepped around Mark Borowiecki and beat Anderson stick side.
Bellemare got the final goal into a wide-open net after Anderson got tangled with Carrier. The Senators challenged unsuccessfully for goaltender interference.
Vegas dominated much of the second period and took a 3-0 lead late when Holden jumped into the play and lifted the puck over Anderson’s right shoulder. It was the well-traveled defenseman’s first goal for Vegas.
Ottawa finally solved Fleury 29 seconds later when the goalie poke-checked Chabot and the puck went right to Duchene. Mike Stone picked up an assist, extending his point streak to five games.
The Knights got two power-play goals in the first period. Marchessault opened the scoring 15 minutes in, and with 20 seconds remaining, Theodore fired a puck from just inside the blue line through traffic and past Anderson.
NOTES: Senators rookie Brady Tkachuk returned after missing the previous nine games with a torn ligament in his left leg. He was held without a point for the first time since his debut. … Ottawa LW Max McCormick was a healthy scratch. … Vegas was without LW Erik Haula, who was injured Tuesday against Toronto.
Golden Knights: At Montreal on Saturday in the third of their four-game trip.
Senators: Visit Tampa Bay on Saturday night in the first of back-to-back games in Florida.